Soft Tissue Sarcoma – Current Management
نویسندگان
چکیده
Progress has been made • The understanding of the biology (cytoand molecular genetics) of the tumour has improved. The identification of the translocation in alveolar RMS has been important, particularly in the identification of those patients who have tumours with a poorer outlook. The t(2;13) and t(1:13) are known to be associated with alveolar disease the former carrying the poorer prognosis, the latter having a prognosis more like that of embryonal disease. The fusion of the PAX 3 and PAX 7 with FKHR has also been demonstrated to occur as a result of these translocations (Barr, Sorensen), allowing for Soft Tissue Sarcoma – Current Management
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تاریخ انتشار 2005